Which of the following technologies is primarily used to facilitate secure transfer of ePHI?

The technology that is primarily used to facilitate the secure transfer of electronic Protected Health Information (ePHI) is encryption. Encryption transforms data into a coded format that can only be read or decrypted by authorized parties who possess the corresponding decryption key. This is essential for protecting sensitive health information during transfer over networks, ensuring that even if data is intercepted, it remains unreadable to unauthorized individuals.

For the context of health information management, the importance of encryption cannot be overstated. It helps healthcare organizations comply with regulations like the Health Insurance Portability and Accountability Act (HIPAA) in the United States and similar regulations in Canada, which mandate the safeguarding of patient data.

While data compression is used to reduce the size of data for easier storage and transmission, it does not secure the information itself. Data mining involves extracting patterns from large datasets, which differs from ensuring secure data transfer. Cloud storage is a method for storing data online but does not inherently include security measures for data transfer unless combined with encryption or other security technologies.

Thus, encryption stands out as the critical technology specifically aimed at securely transferring ePHI, making it the correct choice.